Factors Associated with Poor Quality of Life in Lung Cancer Patients Undergoing Chemotherapy in Erbil City

Authors

  • Dler Hamad Ismael Department of Nursing, College of Nursing, Hawler Medical University, Erbil, Iraq.

DOI:

https://doi.org/10.15218/ejnm.2023.09

Keywords:

Quality of life, Functional assessment of cancer therapy lung cancer subscale, Chemotherapy

Abstract

Background and aims: Lung cancer is one of the most prevalent types of cancer in the world, and the aim of the study was to determine the quality of life. and its related factors in lung cancer patients undergoing chemotherapy.

Methods: A descriptive cross-sectional study design was conducted in Iraq in 2022 on 100 cancer patients undergoing chemotherapy who were randomly collected in Rizgary Teaching Hospital and Nanakaly Hospital for blood disease and cancer. The instrument used for data collection consisted of demographic and medical data (age, gender, educational level, marital status, occupation, economic status, residency, cigarette smoking, family history, stages of lung cancer, and types of lung cancer), another section was the functional assessment of cancer therapy-lung questionnaire (FACT-L), specifically designed for the measurement of quality of life in patients with lung cancer.  Categorical data were presented as frequency and percentage and the mean± SD was calculated for continuous data, independent t-test, and Chi-square test was also used; Binary logistic regression was run to determine the effect of the predictors on poor quality of life in lung cancer patients a P-value ≤0.05 was considered statistically significant.

Results: The overall quality of life was poor (59%), the mean± SD for Functional Assessment of Cancer Therapy Lung Cancer Subscale (FACT-L) was 66.19 ± 10.54, and Trial Outcome Index (TOI) was 39.77±5.51, The following variables were associated with a poor quality of life: age >50 (P-value =0.020, OR= 2.47), female (P-value =0.006, OR= 3.02), uneducated (P-value =0.0005, OR= 1.86), ex-smoker (P-value =0.040, OR= 2.14), insufficient income (P-value =0.037, OR= 2.69).

Conclusion: The quality of life of lung cancer was lower in physical well-being, functioning well-being, and lung cancer subscale compared to social/family well-being, and emotional well-being, as generally, the quality of life of most lung cancer patients was poor.

Metrics

Metrics Loading ...

References

Wong MCS, Lao XQ, Ho KF, Goggins WB, Tse SLA. Incidence and mortality of lung cancer: global trends and association with socioeconomic status. Sci Rep 7, 14300 2017; doi:org/10.1038/s41598-017-14513-7

Fitzmaurice C, Abate D, Abbasi N, Abbastabar H, Abd-Allah F, Abdel-Rahman O et al. Global, regional, and national cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life-years for 29 cancer groups, 1990 to 2017: A Systematic Analysis for the Global Burden of Disease Study. JAMA Oncol. 2019; 5, 1749-68. doi: 10.1001/jamaoncol.2019.2996.

Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018; 68(6):394-24. doi: 10.3322/caac.21492

Khoshnaw N, Mohammed HA, Abdullah DA. Patterns of Cancer in Kurdistan - Results of Eight Years Cancer Registration in Sulaymaniyah Province-Kurdistan-Iraq. Asian Pac J Cancer Prev. 2015;16(18):8525-31. doi: 10.7314/apjcp.2015.16.18.8525.

Reale ML, De Luca E, Lombardi P, Marandino L, Zichi C, Pignataro D, et al . Quality of life analysis in lung cancer: A systematic review of phase III trials published between 2012 and 2018. Lung Cancer. 2020; 139:47-54. doi: 10.1016/j.lungcan.2019.10.022. Epub 2019 Oct 31.

Ravasco P. Nutrition in Cancer Patients. J Clin Med. 2019; 8(8):1211. doi: 10.3390/jcm8081211.

Fitch KV and Pyenson BS. Cancer Patients Receiving Chemotherapy: Opportunities for Better Management; 2010 Available from https://us.milliman.com/en/insight/research / health/ cancer-patients-receiving-chemotherapy-opportunities-for-better-management/

Rashid YA, Ghafoor ZA, Masood N, Mehmood T, Awan S,Ansar T, et al. Psychosocial impact of cancer on adult patients. J Pak Med Assoc. 2012;62(9):905-9. PMID: 23139973.

Bovero A, Sedghi NA, Opezzo M, Botto R, Pinto M, Ieraci V, et al. Dignity-related existential distress in end-of-life cancer patients: prevalence, underlying factors, and associated coping strategies. Psycho- Oncology. 2018;27:2631–2637. doi: 10.1002/pon.4884.

Cella D, Chang CH. A discussion of item response theory and its applications in health status assessment. Med Care. 2000;38(9 Suppl):II66-72. doi: 10.1097/00005650-200009002-00010.

Torre LA, Siegel RL, Jemal A. Lung Cancer Statistics. Adv Exp Med Biol. 2016;893:1-19. doi: 10.1007/978-3-319-24223-1_1.

Kim HJ, Choi CM, Kim SG. The younger pa-tients have more better prognosis in lim-ited disease small cell lung cancer. Tuberc Respir Dis. 2016;79:274–281 doi: 10.4046/trd.2016.79.4.274

Al-Khateeb Z, Mahdi L. Prevalence of Lung Cancer in Al Najaf Governorate Registered in Middle Euphrates Oncology Center during 2019 and 2020. J Fac Med Bagdad . 2022 ;64(1):22-30. doi:org/10.32007/jfacmedbagdad. 6411887

Akl YM, Emam RH, Sabry IM, Ali AA. Clini-co‑pathological profileof bronchogenic carcinoma cases presented to chest department, CairoUniversity in the last 10 years. Egypt J Chest Dis 2013;62:705‑12. doi.org/10.1016/j.ejcdt.2013.09.019.

Chagani P, Parpio Y, Gul R, Jabbar AA. Qual-ity of Life and Its Determinants in Adult Cancer Patients Undergoing Chemotherapy Treatment in Pakistan. Asia Pac J Oncol Nurs. 2017 Apr-Jun;4(2):140-146. doi: 10.4103/2347-5625.204499.

Evans CJ, Trudeau E, Mertzanis P, Marquis P, Peña BM, Wong J, et al . Development and validation of the Pain Treatment Satisfaction Scale (PTSS): a patient satisfaction questionnaire for use in patients with chronic or acute pain. Pain. 2004;112(3):254-266. doi: 10.1016/j.pain.2004.09.005.

Guvencli M, Yalniz E, Komurcuoglu B, Erbaycu AE 2, Karakurt G The Impact of Chemotherapy on the EORTC QLQ-C30 and LC-13 Quality of Life Scales in Patients with Lung CancerTepecik Eğit Hast Derg. 2021; 31(3): 344-354 | doi: 10.5222/terh.2021.73626

Atkins GT, Kim T, Munson J. Residence in Rural Areas of the United States and Lung Cancer Mortality. Disease Incidence, Treatment Disparities, and Stage-Specific Survival. Ann Am Thorac Soc. 2017;14(3):403-411. doi: 10.1513/AnnalsATS.201606-469OC.

Toubat O, Atay SM, Kim AW, Ding L, Farias AJ, Ebner PJ etal. Disparities in Guideline-Concordant Treatment for Pathologic N1 Non-Small Cell Lung Cancer. Ann Thorac Surg. 2020;109:1512-20. doi: 10.1016/j.athoracsur.2019.11.059

Dimunová L, Dankulincova V, Zuzana M, Jana B, Relationship between quality of life of lung cancer patients and smoking. Central European Journal of Nursing and Midwifery.2018; 9. 812. doi:10.15452/CEJNM.2018.09.0009

Aydoğan B, Göksel T, Erbaycu A, Öz A, Pinar C, Gürsul K, etal. The Psychometric Properties and Clinical Use of the Turkish Version of the Functional Assessment of Cancer Thera-py–Lung (FACT-L) Scale. J Basic Clin Health Sci 2019; 3:139-144 .doi.org/10.30621/jbachs.2019.652

Zhang Z, Chen A, Xie F, Li X, Hu G, Lin G. Low prognostic nutrition index predicts poorer quality of life in late-stage lung cancer. Ann Palliat Med. 2020;9(6):3976-3984. doi: 10.21037/apm-20-1892.

Ruano-Raviña A, Provencio M, Calvo de Juan V, Carcereny E, Moran T, Rodriguez-Abreu D, etal . Lung cancer symptoms at diagnosis: results of a nationwide registry study. ESMO Open. 2020;5(6):e001021. doi: 10.1136/esmoopen-2020-001021.

Larsson M, Ljung L, Johansson BB. Health-related quality of life in advanced non-small cell lung cancer: correlates and comparisons to normative data. Eur J Cancer Care (ENGL). 2012 ;21(5):642-9. doi: 10.1111/j.1365-2354.2012.01346.x. Epub 2012 Apr 23.

Kuon J, Vogt J, Mehnert A, Alt-Epping B, van Oorschot B, Sistermanns J et al. Symptoms and Needs of Patients with Advanced Lung Cancer: Early Prevalence Assessment. Oncol Res Treat. 2019;42(12):650-659. doi: 10.1159/000502751. Epub 2019 Oct 21.

Iyer S, Roughley A, Rider A, Taylor-Stokes G. The symptom burden of non-small cell lung cancer in the USA: a real-world cross-sectional study. Support Care Cancer. 2014;22(1): 181–7. doi: 10.1007/s00520-013-1959-4. Epub 2013 Sep 12.

Iyer S, Taylor-Stokes G, Roughley A. Symptom burden and quality of life in advanced non-small cell lung cancer patients in France and Germany. Lung Cancer. 2013 Aug; 81(2): 288–93. doi: 10.1016/j.lungcan.2013.03.008. Epub 2013.

Downloads

Published

2023-05-30

How to Cite

1.
Ismael DH. Factors Associated with Poor Quality of Life in Lung Cancer Patients Undergoing Chemotherapy in Erbil City. Erbil j. nurs. midwifery [Internet]. 2023 May 30 [cited 2024 Jun. 18];6(1):74-83. Available from: https://ejnm.hmu.edu.krd/index.php/ejnm/article/view/275

Issue

Section

Original Articles